Comparative analysis of antibacterial activity of fatty acid from Vietnamese coconut oils produced by hot-extracted and cold-pressing methods
Tóm tắt: 82
| 
PDF: 82 
##plugins.themes.academic_pro.article.main##
Author
Từ khóa:
fatty acid
coconut oil
antibacterial activity
Staphylococcus aureus
cold-pressed extraction
Tóm tắt
This study investigated the antibacterial activity of fatty acids (FAs) extracted from coconut oil against Staphylococcus aureus and Methicillin-resistant S. aureus (MRSA). The FAs exhibited inhibitory effects at concentrations ≥5%, producing inhibition zones of 4 mm and above. Increasing concentration did not yield a proportional enhancement, indicating a non–dose-dependent effect. MRSA displayed slightly greater susceptibility than S. aureus at equivalent concentrations. Significant differences among concentrations were confirmed (p < 0.01). Although overall activity was comparable between cold-pressed (CCO) and hot-extracted coconut oil (HCO), FAs derived from CCO showed stronger inhibition, with minimum inhibitory concentrations (MICs) of 0.39% for both strains, compared to 0.78% for HCO against S. aureus. The superior efficacy of CCO-derived FAs likely reflects better preservation of medium-chain fatty acids—particularly lauric, capric, and caprylic acids—known for antimicrobial properties. These results highlight the influence of processing methods on the antibacterial efficacy of coconut oil–derived fatty acids.
Tài liệu tham khảo
-
[1] T. K. Hoe, “The current scenario and development of the coconut industry”, J. Trop. Agric., vol. 94, pp. 413–426, Dec. 2018.
[2] S. Ahuja, S. Ahuja, and U. Ahuja, “Coconut - History, uses, and folklore”, Asian Agrihist., vol. 18, pp. 221–248, Jan. 2014.
[3] A. Shirwaikar, “Coconut oil - A review of potential applications”, Hygeia J. D. Med., vol. 7, pp. 34–41, Oct. 2015.
[4] M. Gandhi, N. Umate, V. Kuchewar, and S. Parwe, “A narrative review on use of virgin coconut oil in dermatology”, J. Indian Syst. Med., vol. 10, p. 86, 2022.
[5] F. A. Deen et al., “Chemical composition and health benefits of coconut oil: an overview”, Journal of the Science of Food and Agriculture, vol. 101, no. 6, pp. 2182–2193, 2021, doi: 10.1002/jsfa.10870.
[6] Y. J. Ng, P. E. Tham, K. S. Khoo, C. Cheng, C. K. Wayne, and P.-L. Show, “A comprehensive review on the techniques for coconut oil extraction and its application”, Bioprocess Biosyst. Eng., vol. 44, no. 9, pp. 1807–1818, 2021, doi: 10.1007/s00449-021-02577-9.
[7] A. M. Marina, Y. B. Che Man, S. A. H. Nazimah, and I. Amin, “Chemical properties of virgin coconut oil”, J. Am. Oil Chem. Soc., vol. 86, no. 4, p. 301, 2009.
[8] S. Abdalla, M. K. Aroua, and L. T. Gew, “A comprehensive review of plant-based cosmetic oils (virgin coconut oil, olive oil, argan oil, and jojoba oil): Chemical and biological properties and their cosmeceutical applications”, ACS Omega, vol. 9, no. 44, pp. 44019–44032, Nov. 2024, doi: 10.1021/acsomega.4c04277.
[9] F. O. Nitbani, Jumina, D. Siswanta, and E. N. Solikhah, “Isolation and antibacterial activity test of lauric acid from crude coconut oil (Cocos nucifera L.)”, Procedia Chem., vol. 18, pp. 132–140, 2016, doi: 10.1016/j.proche.2016.01.021.
[10] A. M. Marina, Y. B. Che Man, S. A. H. Nazimah, and I. Amin, “Antioxidant capacity and phenolic acids of virgin coconut oil”, Int. J. Food Sci. Nutr., vol. 60, p. 114, 2009.
[11] Z. A. Zakaria, M. N. Somchit, A. M. Mat Jais, L. K. Teh, M. Z. Salleh, and K. Long, “In vivo antinociceptive and anti-inflammatory activities of dried and fermented processed virgin coconut oil”, Med. Princ. Pract., vol. 20, no. 3, p. 231, 2011.
[12] V. Bhardwaj, “Antimicrobial potential of Cocos nucifera (coconut) oil on bacterial isolates”, in Advances in Microbiology, Infectious Diseases and Public Health, vol. 20, G. Donelli, Ed. Cham, Switzerland: Springer, 2025, pp. 1–8, doi: 10.1007/5584_2023_786.
[13] S. R. Varma et al., “In vitro anti-inflammatory and skin protective properties of virgin coconut oil”, J. Tradit. Complement. Med., vol. 9, no. 1, pp. 5–14, 2019, doi: 10.1016/j.jtcme.2017.06.012.
[14] K. G. Nevin and T. Rajamohan, “Effect of topical application of virgin coconut oil on skin components and antioxidant status during dermal wound healing in young rats”, Skin Pharmacol. Physiol., vol. 23, no. 6, pp. 290–297, 2010.
[15] E. Zainodin, N. Rashidi, H. A. Mutalib, B. Ishak, and R. Ghazali, “Antioxidant properties of virgin coconut oil and its cytotoxicity towards human keratinocytes”, Nat. Prod. Commun., vol. 19, Dec. 2024, doi: 10.1177/1934578X241309739.
[16] V. Verallo-Rowell, K. Dillague, and B. Syah-Tjundawan, “Novel antibacterial and emollient effects of coconut and virgin olive oils in adult atopic dermatitis”, Dermatitis, vol. 19, pp. 308–315, Nov. 2008, doi: 10.2310/6620.2008.08052.
[17] G. Vásquez-Vereau and G. Guardia-Méndez, “Antibacterial effect of coconut oil (Cocos nucifera) on Streptococcus mutans ATCC 25175: An in vitro study”, Int. J. Odontostomatol., vol. 15, pp. 922–927, Dec. 2021, doi: 10.4067/S0718-381X2021000400922.
[18] D. C. Widianingrum, C. T. Noviandi, and S. I. O. Salasia, “Antibacterial and immunomodulator activities of virgin coconut oil (VCO) against Staphylococcus aureus”, Heliyon, vol. 5, no. 10, p. e02612, 2019, doi: 10.1016/j.heliyon.2019.e02612.
[19] S. P. López, M. F. Fernández, and L. R. Martínez, “Anti-inflammatory and antimicrobial efficacy of coconut oil for periodontal pathogens: A triple-blind randomized clinical trial”, Clin. Oral Investig., vol. 29, Mar. 2025, doi: 10.1007/s00784-025-06267-8.
[20] J. J. Kabara, D. M. Swieczkowski, A. J. Conley, and J. P. Truant, “Fatty acids and derivatives as antimicrobial agents”, Antimicrob. Agents Chemother., vol. 2, no. 1, pp. 23–28, 1972, doi: 10.1128/aac.2.1.23.
[21] Y. Permata, J. Silalahi, and E. De Lux Putra, “Antibacterial activity of hydrolyzed virgin coconut oil”, Asian J. Pharm. Clin. Res., vol. 7, pp. 90–94, Feb. 2014.
[22] N. Van, T. Le, P. Ngoc Hoa, and L. Tran, “Antibacterial activity of free fatty acids from hydrolyzed virgin coconut oil using lipase from Candida rugosa”, J. Lipids, vol. 2017, pp. 1–7, Nov. 2017, doi: 10.1155/2017/7170162.
[23] N. T. B. Van et al., “In vitro antibacterial activity of the extract from Ampelopsis cantoniensis (chè dây) collected in Da Nang against Staphylococcus aureus isolated from patients with skin infections”, TNU Journal of Science and Technology, vol. 227, no. 10, pp. 235–242, Jul. 2022, doi: 10.34238/tnu-jst.5869.
[24] L. M. Sargent, E. Sgriccia, and E. A. Johnson, “Antimicrobial properties of short-chain fatty acids against Escherichia coli and Salmonella Typhimurium”, J. Food Prot., vol. 66, no. 4, pp. 570–575, 2003.
[25] T. B. Gouda, M. Kumar, S. Geethanjali, V. Vani, and J. Suresh, “A comprehensive review of virgin coconut oil: Extraction methods and diverse applications”, 2024, Horizon e-Publishing Group. doi: 10.14719/pst.5524.
[26] D. O. Ogbolu, A. A. Oni, O. A. Daini, and A. P. Oloko, “In vitro antimicrobial properties of coconut oil on Candida species in Ibadan, Nigeria”, J. Med. Food, vol. 10, no. 2, pp. 384–387, Jun. 2007.
Xem thêm
##plugins.themes.academic_pro.article.sidebar##
Đã Xuất bản
Sep 30, 2025
Download
Cách trích dẫn
My, D. N. T., N. T. Y. Phuong, H. H. Viet, P. T. Cuc, và L. L. T. Tram. “Comparative Analysis of Antibacterial Activity of Fatty Acid from Vietnamese Coconut Oils Produced by Hot-Extracted and Cold-Pressing Methods”. Tạp Chí Khoa học Và Công nghệ - Đại học Đà Nẵng, vol 23, số p.h 9B, Tháng Chín 2025, tr 17-21, doi:10.31130/ud-jst.2025.23(9B).497.
