Analysis and treatment of trimethoprim residues in water by γ-irradiation
Abstract: 44
| 
PDF: 30 
##plugins.themes.academic_pro.article.main##
Author
Keywords:
analysis
antibiotic residues
gamma-irradiation
trimethoprim
water treatment and reuse
Abstract
Trimethoprim (TMP) is widely applied in veterinary and also frequently prescribed together with sulfa-methoxazole (SMX) for human medicine. Therefore TMP residues accumulated in agricultural as well as municipal waste water further contaminate surface water. In this paper, the capability of HPLC/UV to detect and quantify TMP residues in water is thoroughly investigated, yielding LOD = 0.06 µM, LOQ = 0.2 µM and very good reproducible calibration line in the concentration range of 2 µM ÷ 100 µM. The resulting procedure is applied to evaluate the capability to treat TMP residues in water (init. 20 µM ÷ 140 µM) by gamma irradiation. Removal yields greater than 99 % are obtained using absorbed doses 0.3 ÷ 3.0 kGy, respectively. Based on the HPLC/UV chromatograms obtained, some aspects of the TMP radio-lytic products in the investigated samples are briefly discussed.
References
-
[1] Sui Q., Cao X., Lu S., Zhao W., Qiu Z., Yu G., Occurrence, sources, and fates of pharmaceu-ticals and personal care products in the groundwater: A review, Emerging Contaminants 1 (2015) 14-24.
[2] Schaefer M.M., Doyle L.A., Fleenor W.E., Johnson M.L., Fate and Transport of Three Pharmaceuticals in the Sacramento–San Joaquin Delta, San Francisco Estuary and Watershed Science 11 (2013) 1-13.
[3] Dinh Q.T., Moreau-Guigon E., Labadie P., Alliot F., Marie-Jeanne T., Blanchard M., Joelle E., Chevreuil M., Fate of antibiotics from hospital and domestic sources in a sewage network, Sci. Total Environ. 575 (2017) 758-766.
[4] Dinh Q.T., Moreau-Guigon E., Labadie P., Alliot F., Marie-Jeanne T., Blanchard M., Chevreuil M., Occurrence of antibiotics in rural catchments, Chemosphere 168 (2017) 483-490.
[5] Shimizu A., Takada H., Koike T., Takeshita A., Saha M., Rinawati, Nakada N., Murata A., Suzuki T., Suzuki S., Nguyen H.C., Bui C.T., Pham H.V., Siringan M.A., Kwan C., Zakaria M.P., Reungsang A., Ubiquitous occurrence of sulfonamides in tropical Asian waters, Science of the Total Environment 452-453 (2013)108-115.
[6] Yin D.P., Liu M.X., Fu H.L., Shu G., Zhou J.Y., Qing X.Y., Wu W.B., Solubility of Trimethoprim in Selected Pure Solvents and (Water + Ethanol/2-Propanol) Mixed-Solvent Systems, J. Chem. Eng. Data 61 (2016) 404-411.
[7] Rajith L., Jissy A.K., Kumar K.G., Datta A., Mechanistic Study for the Facile Oxidation of Trimethoprim on a Manganese Porphyrin Incorporated Glassy Carbon Electrode, J. Phys. Chem. C 115 (2011) 21858–21864.
[8] Zhang Y.L., Lin S.S., Dai C.M., Shi L., Zhou X.F., Sorption–desorption and transport of trime-thoprim and sulfonamide antibiotics in agricultural soil: effect of soil type, dissolved organic matter, and pH, Environ. Sci. Pollut. Res. 21 (2014) 5827-5835.
[9] Ji Y. Xie W., Fan Y., Shi Y., Kong D., Lu J. (2016), Degradation of trimethoprim by thermo-activated persulfate oxidation: Reaction kinetics and transfor-mation mechanisms, Chem. Eng. J. 286 (2016) 16–24.
[10] Sirtori C., Aguera A., Gernjak W., Malato S. (2010), Effect of water matrix composition on Trimethoprim solar photodegradation kinetics and pathways, Water Research 44 (2010) 2735-2744.
[11] Kim H.Y., Kim T.H., Yu S., Photolytic degradation of sulfamethoxazole and trimethoprim using UV-A, UV-C and vacuum-UV (VUV), J. Environ. Sci. & Health A 50 (2015) 292–300.
[12] Zhang R., Sun P., Boyer T.H., Zhao L., Huang C.H., Degradation of Pharmaceuticals and Metabolite in Synthetic Human Urine by UV, UV/H2O2, and UV / PDS, Environ. Sci. Technol. 49 (2015) 3056-3066.
[13] Zhang R., Yang Y., Huang C.H., Li N., Liu H., Zhao L., Sun P., UV/H2O2 and UV/PDS Treatment of Tri-methoprim and Sulfamethoxazole in Synthetic Human Urine: Transformation Products and Toxicity, Environ. Sci. Technol. 50 (2016) 2573–2583
[14] Luo X., Zheng Z., Greaves J., Cooper W.J., Song W., Trimethoprim: Kinetic and mechanistic consideration in photochemical environmental fate and AOP treatment, Water Research 46 (2012) 1327-1336.
[15] Zhang Z., Yang Q., Wang J., Degradation of thrimethoprim by gamma irradiation in the presence of persulfate, Rad. Physics Chem. 127 (2016) 85-91.
[16] Le D.N., Le T.T.T., Mai V.T.T., Huynh K.L., Ngo M.T., Transformation Products of Aqueous Sulfame-thoxazole by 60Co Gamma Irradiation - A Combined Computational and Experimental Study, Proc. 5th World Conf. Appl. Sci. Eng. & Technol., (2016) 64-69, ISBN 13:978-81-930222-2-1.
[17] Ngo M.T., Hoang M.N., Tran T.M.T., Radiolysis of 1-naphthol in aqueous solutions, J. Radioanal. Nucl. Chem. 286 (2010) 287-293.
[18] Wojnarovitz L., Takacs E., Wastewater treatment with ionizing radiation, J. Radioanal. Nucl. Chem. 311 (2017) 973-981.
Read more
##plugins.themes.academic_pro.article.sidebar##
Published
Dec 31, 2017
Download
How to Cite
Nam D. Le, Thang M. Ngo. “Analysis and Treatment of Trimethoprim Residues in Water by γ-Irradiation”. The University of Danang - Journal of Science and Technology, vol. 12, no. 121, Dec. 2017, pp. 15-18, https://jst-ud.vn/jst-ud/article/view/78.
