Survey the proportion and antibiotic sensitivity of methicillin-resistant staphylococcus aureus among patients in Danang Oncology Hospital

https://doi.org/10.31130/ud-jst.2023.314E
Tóm tắt: 97 | PDF: 84

##plugins.themes.academic_pro.article.main##

Author

  • Le Ngoc Uyen Thi
    The University of Danang - VNUK Institute for Research and Executive Education, Danang, Vietnam
    Le Ngoc Phu Thien
    The University of Danang - VNUK Institute for Research and Executive Education, Danang, Vietnam
    Le Hai Tan
    The University of Danang - VNUK Institute for Research and Executive Education, Danang, Vietnam
    Duong Nguyen Hoa Bao
    The University of Danang - VNUK Institute for Research and Executive Education, Danang, Vietnam
    Nguyen Gia Phuc
    The University of Danang - VNUK Institute for Research and Executive Education, Danang, Vietnam
    Nguyen Thanh Hoi
    The University of Danang - Center for Continuing Education, Danang, Vietnam
    Giang Thi Kim Lien
    The University of Danang - VNUK Institute for Research and Executive Education, Danang, Vietnam
    Nguyen Pham Thanh Nhan
    Danang Oncology Hospital, Danang, Vietnam
    Nguyen Thi Thuy Duong
    The University of Danang - VNUK Institute for Research and Executive Education, Danang, Vietnam

Từ khóa:

Staphylococcus aureus
MRSA
MSSA
kháng sinh
đề kháng kháng sinh

Tóm tắt

In this study, 134 patients including 80 adult men and 54 women treated at Danang Oncology Hospital from January 2019 to July 2021 had specimen culture results found Staphylococcus aureus was investigated. All study patient data was collected according to an established uniform form on Microsoft Excel spreadsheet software and processed by Python programming language. We found that 76.1% of patients infected with S. aureus during this time were MRSA. Of which, 100% MRSA and MSSA isolates were resistant to Amoxicillin, 61.2% to Cefuroxime. Multi-resistance and broad-spectrum multi-resistance to other antibiotics belonging to the Carpapenem, Quinolone and Aminoglycoside groups were recorded in most isolated S. aureus. The results showed that S. aureus causing bacterial infection at Danang Oncology Hospital during the survey period had a high antibiotic resistance rate.

Tài liệu tham khảo

    [1] J. M. Raineri et al., “Staphylococcus aureus populations from the gut and the blood are not distinguished by virulence traits - a critical role of host barrier integrity”, Microbiome, vol. 10, no. 1, pp. 1-23, 2022, doi: 10.1186/s40168-022-01419-4.
    [2] Y. C. Tong, J. S. Davis, E. Eichenberger, T. L. Holland, and V. G. Fowler, “Staphylococcus aureus infections: Epidemiology, pathophysiology, clinical manifestations, and management”, Clin. Microbiol. Rev., vol. 28, no. 3, pp. 603-661, 2015, doi: 10.1128/CMR.00134-14.
    [3] J. G. Pollitt, P. T. Szkuta, N. Burns, and S. J. Foster, “Staphylococcus aureus infection dynamics”, PLoS Pathog., vol. 14, no. 6, pp. 1–27, 2018, doi: 10.1371/journal.ppat.1007112.
    [4] M, K. Kulhankova, C. S. Stach, B. G. Vu, and W. Salgado-pabón, “Phenotypes and Virulence among Staphylococcus aureus USA100, USA200, USA300, USA400, and USA600 Clonal Lineages”, vol. 1, no. 3, pp. 1–15, 2016, doi: 10.1128/mSphere.00071-16.Editor.
    [5] Schaumburg, A. S. Alabi, G. Peters, and K. Becker, “New epidemiology of Staphylococcus aureus infection in Africa”, Clin. Microbiol. Infect., vol. 20, no. 7, pp. 589–596, 2014, doi: 10.1111/1469-0691.12690.
    [6] Hassoun, P. K. Linden, and B. Friedman, “Incidence, prevalence, and management of MRSA bacteremia across patient populations-a review of recent developments in MRSA management and treatment”, Crit. Care, vol. 21, no. 1, p. 211, 2017, doi: 10.1186/s13054-017-1801-3.
    [7] V. Nguyen et al., "Appropriate antibiotic use and associated factors in vietnamese outpatients. Healthcare", Healthcare., vol. 9, no. 6, pp. 693–705, 2021, https://doi.org/10.3390/healthcare9060693
    [8] Mensa et al., “Recommendations for antibiotic selection for severe nosocomial infections”, Rev. Esp. Quimioter., vol. 34, no. 5, pp. 511–524, 2021, doi: 10.37201/req/126.2021.
    [9] S. Lee et al., “Methicillin-resistant Staphylococcus aureus”, Nat. Rev. Dis. Prim., vol. 4, no. 5, pp. 1–23, 2018, doi: 10.1038/nrdp.2018.33.
    [10] V. I. Rolston, “Infections in Cancer Patients with Solid Tumors: A Review”, Infect. Dis. Ther., vol. 6, no. 1, pp. 69–83, 2017, doi: 10.1007/s40121-017-0146-1.
    [11] Arora, A. Saroch, N. Verma, and P. Gupta, “Metastatic seeding in Staphylococcus infection”, BMJ Case Rep., vol. 14, no. 2, pp. 2020–2021, 2021, doi: 10.1136/bcr-2020-240301.
    [12] Tiwari, M. Sahu, B. Rautaraya, T. Karuna, S. R. Mishra, and S. Bhattacharya, “Prevalence of methicillin-resistant Staphylococcus aureus and its antibiotic susceptibility pattern in a tertiary care hospital”, J. Indian Med. Assoc., vol. 109, no. 11, pp. 800–801, 2011.
    [13] Hu et al., “Combinations of β-lactam or aminoglycoside antibiotics with plectasin are synergistic against methicillin-susceptible and methicillin-resistant Staphylococcus aureus”, PLoS One, vol. 10, no. 2, pp. 1–15, 2015, doi: 10.1371/journal.pone.0117664.
    [14] K. S. Saba, J. K. Amenyona, and S. W. Kpordze, “Prevalence and pattern of antibiotic resistance of Staphylococcus aureus isolated from door handles and other points of contact in public hospitals in Ghana”, Antimicrob. Resist. Infect. Control, vol. 6, no. 1, pp. 1–6, 2017, doi: 10.1186/s13756-017-0203-2.
    [15] Kayili and P. Sanlibaba, “Prevalence, characterization and antibiotic resistance of Staphylococcus aureus isolated from traditional cheeses in Turkey”, Int. J. Food Prop., vol. 23, no. 1, pp. 1441–1451, 2020, doi: 10.1080/10942912.2020.1814323.
Xem thêm

##plugins.themes.academic_pro.article.sidebar##

Đã Xuất bản

Dec 31, 2023
Download
PDF (English)
Cách trích dẫn
Thi, L. N. U., L. N. P. Thien, L. H. Tan, D. N. H. Bao, N. G. Phuc, N. T. Hoi, G. T. K. Lien, N. P. T. Nhan, và N. T. T. Duong. “Survey the Proportion and Antibiotic Sensitivity of Methicillin-Resistant Staphylococcus Aureus Among Patients in Danang Oncology Hospital”. Tạp Chí Khoa học Và Công nghệ - Đại học Đà Nẵng, vol 21, số p.h 12.1, Tháng Chạp 2023, tr 113-6, doi:10.31130/ud-jst.2023.314E.

##plugins.themes.academic_pro.article.details##