Study on biological activity of fucoidan extracted from brown marine algae (Sargassum cristaefolium) collected in the sea of Vung Tau, Viet Nam
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Keywords:
α-amylase inhibitor
anti-inflammatory
anti-UVB
fucoidan
Sargassum cristaefolium
Abstract
This study investigated the chemical composition, antioxidant, α-amylase inhibitory, anti-inflammatory, antibacterial, and UV-B-protective activities of crude fucoidan extract from brown algae Sargassum cristaefolium. The results showed that fucoidan extract exhibited antioxidant activity in the ABTS method with an IC50 value of 332.92 ± 13.89 μg/mL, inhibiting the activity of the α-amylase enzyme with an IC50 of 975.73 ± 43.9 μg/mL. The ability to reduce the denaturation of bovine serum albumin protein of the extract was investigated for an IC50 value of 12091.16 ± 487.42 μg/mL. Survey results showed that fucoidan has not yet shown anti-bacterial activity against 4 strains of bacteria that cause human disease. In addition, the UV-B protection ability was investigated at a concentration of 1000 μg/mL with an SPF value of 21.81 ± 0.13. The investigated results show that crude fucoidan extract from Sargassum cristae folium has potential applications in the cosmetic industry and pharmaceuticals.
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Published
Jan 31, 2025
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How to Cite
Nam, V. B. N., V. M. Nguyên, D. Q. Việt, M. T. D. Trang, N. T. K. Huê, Đặng H. H. Anh, and T. T. Mến. “Study on Biological Activity of Fucoidan Extracted from Brown Marine Algae (Sargassum Cristaefolium) Collected in the Sea of Vung Tau, Viet Nam”. The University of Danang - Journal of Science and Technology, vol. 23, no. 1, Jan. 2025, pp. 65-70, doi:10.31130/ud-jst.2025.394.
